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The 2022 CNBC Disruptor 50 list: Meet the next generation of Silicon Valley

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In the tenth annual Disruptor 50 list, CNBC highlights private companies that grew through the ups and downs of the pandemic and are poised to meet increasing economic and consumer challenges.

All told, these firms have raised a half-trillion dollars in venture capital. At least 41 are unicorns, with valuations of $1 billion or more – 14 are valued at over $10 billion. But becoming a unicorn has become all too common, and as market volatility pressures valuations in both public and private markets, other stats stand out:

Forty of the companies have a social or environmental purpose that is core to their business model. Ten of this year’s Disruptors are from the logistics sector, tackling the broken global supply chain that has fueled four-decade high inflation. Eight are reducing costs in a bloated health-care system and reaching underserved populations. Several more are dedicated to the climate crisis. Nine of this year’s Disruptors have a female founder. Sixteen feature CEOs from racial and ethnic minorities.

The 50 companies selected using the proprietary Disruptor 50 methodology have raised over $56 billion in venture capital, according to PitchBook, at an implied Disruptor 50 valuation of more than $552 billion.

1FlexportOverwhelming the supply chain bottleneck2BrexThe start-up world’s finance department3Lineage LogisticsOn top of the global food supply’s temperature4CanvaThe feature presentation5Guild EducationWork. Study.6ConvoyTrucking as we’ve known it stops here7Blockchain.comWeb3’s dot com8StripeMaking the internet pay9Dapper LabsThe shot Michael Jordan and Kevin Durant are taking on decentralization10Pony.aiHand over the reins.11Checkout.comA rival to the Stripe swipe12ChimeA challenger bank in a challenging fintech market13DiscordHow digital natives converse14Flock FreightFully loaded15MedableThe virtual clinical trial16TruepillThe infrastructure for online pharmacy17Arctic WolfA cyber defender from up north18CloudTrucksBig ideas for the Big Road19Maven ClinicPutting women first in health20Monarch Tractor1 driver. 8 tractors. All electric.21FanaticsTaking sports merch into the metaverse22TalaThe world’s local lender23Anduril IndustriesEngineering an autonomous military arsenal24WorkatoOffice work automated25LaceworkCybercrime’s lie detector26SomatusKidney care without the dialysis centers27GopuffAll your instant needs fulfilled28Virta HealthDon’t treat diabetes; reverse it.29ZiplineA life-saving drone, with a Walmart side hustle30CarbonCureCarbon to concrete31J?stoMexico’s answer to Walmart, and FreshDirect, and Gopuff32Biobot AnalyticsA wastewater virus hunter33AirtableThe code for every knowledge worker34DatabricksThe start-up world’s biggest data bet35DataRobotA one-trillion predictions market maker36Relativity SpaceAn Elon Musk reusable rocket competitor37NEXT InsuranceDigital small business insurance38RoPlanning to be a digital health survivor39AirspaceCritical on-demand delivery for the pandemic era40ThrasioA consumer products giant for the digital age.41CybereasonA bird’s eye view42BlocPowerBuilding net-zero cities43?URAThe one ring to rule wearables44MoonPayThe biggest celebrity bet on crypto45ZumSchool bus magic46ExotecFrance’s warehouse robot unicorn47PlaidA bridge from fintech to bank48Cityblock HealthHealthtech for low-income America49Impossible FoodsFrom plant-based fad to fixture50EnvoyBack to the office of the future

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